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The Relationship Between Age and Histopathological Patterns of Endometrial Hyperplasia at Dr. H. Abdul Moeloek Regional Hospital, Lampung Province, 2021–2024

Authors

  • Salsa Nurfajri Yuska

    Lampung University

  • Nur Ayu Virginia Irawati

    Lampung University

  • Nurul Islamy

    Lampung University

  • Indri Windarti

    Lampung University

DOI:

https://doi.org/10.53366/jimki.v12i3.1019

Keywords:

Age; Endometrial hyperplasia; Histopathology

Abstract

Background: Endometrial hyperplasia is a proliferative condition with potential to develop into precancerous lesions. Hormonal imbalance, particularly estrogen dominance without progesterone opposition, is considered a key factor in its development. This study aimed to analyze the relationship between age and histopathological patterns of endometrial hyperplasia at Dr. H. Abdul Moeloek Regional Hospital, Lampung Province. Method: An analytical observational study with a cross-sectional design was conducted using medical records of patients with endometrial hyperplasia from 2021 to 2024. Total sampling was used to include all eligible cases. Fisher’s exact test was applied to examine the association between age and histopathological type. Results: Of the 31 included samples, most patients were aged ?45 years, with non-atypical hyperplasia being the most common. Analysis showed a significant association between age and histopathological type, with a higher prevalence of atypical hyperplasia observed in older patients. Discussion: Age plays a significant role in the histopathological patterns of endometrial hyperplasia. Hormonal changes during perimenopause and postmenopause contribute to an increased risk of atypical lesions with advancing age. Conclusion There is a significant association between age and the histopathological patterns of endometrial hyperplasia, with older age groups showing a higher proportion of atypical hyperplasia.

 

Author Biographies

  • Salsa Nurfajri Yuska, Lampung University

    Medical Education, Faculty of Medicine, University of Lampung, Bandar Lampung

  • Nur Ayu Virginia Irawati, Lampung University

    Department of Anatomy, Faculty of Medicine, University of Lampung, Bandar Lampung

  • Nurul Islamy, Lampung University

    Department of Obstetrics and Gynecology, Faculty of Medicine, University of Lampung, Bandar Lampung

  • Indri Windarti, Lampung University

    Department of Anatomical Pathology, Faculty of Medicine, University of Lampung, Bandar Lampung

References

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Published

2026-01-14

Issue

Vol. 12 No. 3 (2026): JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Vol. 12.3 (2026)

Section

Research Article

License

Copyright (c) 2026 Salsa Nurfajri Yuska, Nur Ayu Virginia Irawati, Nurul Islamy, Indri Windarti

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

How to Cite

The Relationship Between Age and Histopathological Patterns of Endometrial Hyperplasia at Dr. H. Abdul Moeloek Regional Hospital, Lampung Province, 2021–2024. (2026). JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia, 12(3), 1240-1248. https://doi.org/10.53366/jimki.v12i3.1019