Comparison Of Neutrophil-Lymphocyte Ratio (NLR) In Patients With Viral And Nonviral Hepatitis At Rsud Undata, Central Sulawesi 2020-2024
DOI:
https://doi.org/10.53366/jimki.v12i3.1055Keywords:
nonviral hepatitis, viral hepatitis, neutrophil lymphocyte ratioAbstract
Abstract (English)
Introduction: Hepatitis is a global health challenge caused by viral and non-infectious factors. Indonesia ranks third worldwide with 18.9 million cases, while Palu City records the highest prevalence of HBsAg-reactive pregnant women. The neutrophil-to-lymphocyte ratio (NLR) is an important inflammatory marker to assess hepatitis severity. This study aimed to analyze differences in NLR values between viral and nonviral hepatitis.
Methods: An observational analytic study with a cross-sectional design was conducted using secondary medical record data of viral and nonviral hepatitis patients at RSUD Undata Central Sulawesi from 2020–2024. A total of 73 patients were included through total sampling. Data were analyzed using the Mann–Whitney test with p<0.05 considered significant.
Results: The median NLR in viral hepatitis patients was 3.3, while in nonviral hepatitis it was 6.7. The Mann–Whitney test revealed a significant difference between the two groups (p<0.001). Higher NLR in nonviral hepatitis indicates a stronger inflammatory response.
Discussion: These findings highlight that NLR reflects distinct inflammatory mechanisms between viral and nonviral hepatitis. Elevated NLR in nonviral hepatitis supports its role as an additional clinical indicator.
Conclusion: There is a significant difference in NLR values between viral and nonviral hepatitis. NLR may serve as an additional parameter to evaluate inflammation and disease severity in hepatitis.
Keywords: Nonviral Hepatitis, Viral Hepatitis, Neutrophil-to-Lymphocyte Ratio
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