The Relationship Between Stress Levels and Irritable Bowel Syndrome Incidence in Female Medical Students Batch 2022 at University of Lampung
DOI:
https://doi.org/10.53366/jimki.v12i3.1057Keywords:
Irritable Bowel Syndrome, Medical Students, Stress LevelsAbstract
Background: Irritable Bowel Syndrome (IBS) is a multifactorial functional gastrointestinal disorder that can be influenced by psychological factors, including stress. Medical students represent a population at high risk of experiencing academic stress, which may trigger or exacerbate IBS symptoms. This study aimed to investigate the relationship between stress levels and the occurrence of IBS among female medical students batch 2022 at the University of Lampung.
Methods: This cross-sectional study involved 60 female students from the class of 2022 who fulfilled the inclusion and exclusion criteria. Stress levels were assessed using the Perceived Stress Scale-10 (PSS-10), while IBS was identified based on the Rome IV criteria. Statistical analysis was conducted using the chi-square test to examine the association between stress levels and IBS occurrence.
Results: A total of 48 respondents (80%) reported moderate-to-high stress levels, while 12 respondents (20%) had low stress levels. Overall, 20 respondents (33.3%) were diagnosed with IBS. The analysis revealed a significant association between stress levels and IBS occurrence (p = 0.040), with a higher proportion of IBS cases observed in the moderate-to-high stress group compared to the low stress group.
Discussion: These findings are consistent with previous literature indicating that stress can influence gastrointestinal function through the brain–gut axis and modulation of the microbiota, thereby increasing the risk of developing IBS symptoms.
Conclusion: Stress levels are significantly associated with the occurrence of IBS among female medical students.
Keywords: Irritable Bowel Syndrome, Medical Students, Stress Levels
References
Arif, T. B., Ali, S. H., Bhojwani, K. D., Sadiq, M., Siddiqui, A. A., Ur-Rahman, A., Khan, M. Z., Hasan, F., & Shahzil, M. Global prevalence and risk factors of irritable bowel syndrome from 2006 to 2024 using the Rome III and IV criteria: a meta-analysis. European journal of gastroenterology & hepatology. 2025.
Perkumpulan Gastroenterologi Indonesia (PGI). Konsensus Nasional Penatalaksanaan Irritable Bowel Syndrome (IBS) dan Dispepsia Fungsional di Indonesia Tahun 2021. Jakarta: PPIP Interna. 2021.
Das, T., Rimti, F. H., Fahid, H. A., Uthso, N. A., & Hossain Hawlader, M. D. Prevalence of IBS and its association with academic stress and dormitory lifestyle among medical students of Bangladesh: A cross-sectional study. Heliyon. 2024; 10(16): 1-9.
Horn, A., Stangl, S., Parisi, S., Bauer, N., Roll, J., Löffler, C., et al. Systematic review with Meta-analysis: Stress-Management Interventions for Patients with Irritable Bowel Syndrome. Stress and Health. 2023; 39(4): 694–707.
Zhang, L., Wang, H., Zhang, Y., Mao, X., Wu, T., Huang, Z., et al. Stress triggers irritable bowel syndrome with diarrhea through a spermidine-mediated decline in type I interferon. Cell Metabolism. 2025; 37(1): 87–103.
Ahani, A. R., Syam, A. F., Putranto, R., & Nugroho, P. Kejadian Sindrom Kolon Iritabel Berdasarkan Kriteria Baru Roma IV pada Mahasiswa Kedokteran dan Faktor-Faktor yang Berhubungan. Jurnal Penyakit Dalam Indonesia. 2022; 9(1): 35-41.
Tang, H. Y., Jiang, A. J., Wang, X. Y., Wang, H., Guan, Y. Y., Li, F., & Shen, G. M. Uncovering the pathophysiology of irritable bowel syndrome by exploring the gut-brain axis: a narrative review. Annals of translational medicine. 2021; 9(14): 1-13.
Lv, Y., Wen, J., Fang, Y., Zhang, H., & Zhang, J. Corticotropin-releasing factor receptor 1 (CRF-R1) antagonists: Promising agents to prevent visceral hypersensitivity in irritable bowel syndrome. Peptides. 2022; 147, 170705.
Hillestad, E. M. R., van der Meeren, A., Nagaraja, B. H., Bjørsvik, B. R., Haleem, N., Benitez-Paez, A., Sanz, Y., Hausken, T., Lied, G. A., Lundervold, A., & Berentsen, B. Gut bless you: The microbiota-gut-brain axis in irritable bowel syndrome. World journal of gastroenterology. 2022; 28(4), 412–431.
Kusumadewi, K. R. T., Yenny, L. G. S., & Aryastuti, A. A. S. A. Hubungan Stres dengan Kejadian Irritable Bowel Syndrome pada Mahasiswa Tahun Pertama Fakultas Kedokteran dan Ilmu Kesehatan Universitas Warmadewa. Aesculapius Medical Journal. 2022; 2(3): 195–199.
Fernanda, E., & Kurniawan, A. Factors Affecting Irritable Bowel Syndrome in Medical Students. 2020; 21(2): 95–98.
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